Mitochondria directly interact with the nuclear pore complex

Data availability

All large datasets have been deposited as raw files: RNA-seq ( GSE325290 ), ChIP–seq ( GSE324951 ), ATAC-seq ( GSE324952 ) and proteomics ( PXD065792 and PXD065793 ). Analysed, curated datasets, required for the conclusions described in this article, can be found in the Supplementary Information . Biological models (CRISPR-edited cell lines and mouse model) are available on request to the corresponding author.  Source data are provided with this paper.

Code availability

The code used in the biophysical model of ATP diffusion is accessible and available in Google Colab ( https://colab.research.google.com/drive/10ufpBhsLk96DidzzFEsj79KGXr2iGR64?usp=sharing ). The code used in phylogenetic analyses of vertebrate RANBP2 is accessible and available in a Github repository ( https://github.com/akwestfall/EvolutionRANBP2 ).

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