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This remarkable therapy could permanently lower bad cholesterol
Slovenia🩺 Health2 hr. ago

This remarkable therapy could permanently lower bad cholesterol

Scientists are on the verge of a medical breakthrough that could revolutionize the treatment of cardiovascular diseases. Initial clinical trial results show that a single infusion of an experimental gene therapy called CTX310 safely and significantly lowers levels of bad LDL cholesterol and triglycerides. This therapy uses CRISPR-Cas9 technology, often referred to as genetic scissors, to target the ANGPTL3 gene in liver cells, effectively 'turning it off' and reducing cholesterol production. The first phase involved fifteen adults with extremely high cholesterol levels unmanageable by existing medications. Results showed a significant drop in cholesterol and triglyceride levels within two weeks, with only mild side effects like weakness and back pain. Researchers remain cautious but hopeful, with plans for further trials to confirm safety and efficacy.

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Večer logoVečerIndependent🔒Center2 hr. ago
This remarkable therapy could permanently lower bad cholesterol

Scientists are on the verge of a medical breakthrough that could revolutionize the treatment of cardiovascular diseases. Initial clinical trial results show that a single infusion of an experimental gene therapy called CTX310 safely and significantly lowers levels of bad LDL cholesterol and triglycerides. This therapy uses CRISPR-Cas9 technology, often referred to as genetic scissors, to target the ANGPTL3 gene in liver cells, effectively 'turning it off' and reducing cholesterol production. The first phase involved fifteen adults with extremely high cholesterol levels unmanageable by existing medications. Results showed a significant drop in cholesterol and triglyceride levels within two weeks, with only mild side effects like weakness and back pain. Researchers remain cautious but hopeful, with plans for further trials to confirm safety and efficacy.

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