Author Correction: Autophagic cell death restricts chromosomal instability during replicative crisis

On 19 June 2026, *Nature* published an official author correction regarding an article titled "Autophagic cell death restricts chromosomal instability during replicative crisis." The correction addressed specific inaccuracies in the methods section of the original paper. Specifically, the P16 antibody referenced in the "Antibodies" subsection was incorrectly labeled as "Abcam ab51243," when in reality, it was the BD Pharmingen Purified Mouse Anti-Human p16 antibody, catalog number 550834. Additionally, the wild-type mCherry–EGFP–LC3B plasmid used in the "Plasmids and transductions" section was misidentified as plasmid number 26477, whereas the correct identifier is plasmid number 22418. These discrepancies were noted due to the age of the article, which prevented direct updates to the original text. Instead, the journal issued this formal notice to clarify the errors without altering the content of the original research findings.

The original article was authored by researchers affiliated with multiple institutions, including the Salk Institute for Biological Studies in La Jolla, California, and the Institute of Human Genetics at the University of Heidelberg in Germany. The lead authorship was shared among Joe Nassour, Robert Radford, Adriana Correia, Javier Miralles Fusté, Brigitte Schoell, Anna Jauch, Reuben J. Shaw, and Jan Karlseder. Correspondence related to the article was directed to Jan Karlseder, who served as the primary contact point for further inquiries about the research. The correction does not impact the scientific validity or conclusions drawn from the study, which focused on the role of autophagy in limiting chromosomal instability during cellular replication crises.

This correction follows similar actions taken earlier in the year regarding another *Nature* article titled "Ontogeny and transcriptional regulation of Thetis cells." On 16 June 2026, the journal published a detailed author correction addressing several data-related issues in the manuscript. One notable error involved the duplication of values in Extended Data Figure 6c, where data points for TCP (pLN 11 weeks) were mistakenly copied from the LTi cell column within the same block. Similarly, for Spleen P12, the first two rows of data for DC1 and DC2 were erroneously duplicated from the pLN P12 block. Furthermore, the column headers for Spleen P12 were transposed, listing "TCP, TC I-IV" instead of "TC I-IV, TCP."

In response to these concerns raised on PubPeer, the authors conducted a thorough review of all figures and their corresponding source data. They discovered additional minor errors confined solely to the source data files, such as a duplicated row of TLP values in Figure 3d and transposed column headers in Extended Data Figures 3, 7d, and 9e. Another issue involved incorrect data transcription in Extended Data Figure 7j, where the values recorded pertained to RORγt MFI instead of FLT3 MFI. All affected source data files were subsequently corrected, although the published figures remained unchanged since they were generated directly from the raw data. To ensure transparency, both the original and corrected figures are now available as supplementary information alongside the revised article.

The authors acknowledged the importance of accuracy in scientific reporting and expressed gratitude to the reader who brought these issues to their attention. They emphasized that despite these corrections, the overall conclusions and interpretations of the study remain intact. The research team includes scientists from various prestigious institutions, such as the Howard Hughes Medical Institute, Weill Cornell Medicine Graduate School of Medical Sciences, and Memorial Sloan Kettering Cancer Center. Notably, Marc Elosua Bayes, one of the contributing authors, has relocated to Boston Children's Hospital, Harvard Medical School, where he continues his research efforts.

Another *Nature* article, "Plasticity and language in the anaesthetized human hippocampus," also underwent a correction on 6 May 2026. The primary issue concerned an error in the time scale depicted in Figure 1e. Initially, the x-axis displayed values ranging from "0, 67, 133, 200" with the label "Time (µs)," but the correct values should have been "0, 0.67, 1.33, 2" with the label "Time (ms)." This discrepancy was promptly rectified in both the HTML and PDF versions of the article. The correction highlights the necessity for precision in presenting experimental results, particularly when dealing with temporal measurements crucial to understanding neural activity patterns.

The research described in this article was conducted by a multidisciplinary team involving experts from departments such as Neurosurgery, Neurology, and Neuroscience at institutions like Baylor College of Medicine, Massachusetts General Hospital, and Rice University. Key contributors include Eric R. Cole, Elizabeth A. Mickiewicz, Shraddha Shah, and others, who collaborated under the supervision of Benjamin Y. Hayden and Sameer A. Sheth. Their work aimed to explore the functional dynamics of the human hippocampus under anesthesia, shedding light on its role in plasticity and language processing. The correction ensures that future readers can rely on accurate representations of the data presented in the study.