FranceResearchers at the International Agency for Research on Cancer (IARC), part of the World Health Organization (WHO), based in Lyon, have identified a new tobacco-related genetic signature linked to various cancers. The carcinogenic substances in cigarette smoke leave characteristic marks in the genome of cells, which can be found in different types of tumors, including tissues not directly exposed to smoke. These substances, such as polycyclic aromatic hydrocarbons (PAHs) present in tar, cause specific DNA mutations that have been systematically studied. In 2016, these mutations were detected in lung and laryngeal cancers, as well as to a lesser extent in liver cancer, through a study comparing the genomes of over 3,000 individuals who smoked or did not smoke.
Bias read (Center): The article discusses scientific research on the health effects of tobacco, focusing on genetic markers in cancer patients. It presents findings from academic and medical institutions without overt ideological framing or biased language. There is no indication of political controversy or partisan sl
