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Pine bark and sponge compounds could counter drug-resistant malaria and babesiosis
United Kingdom🏛️ PoliticsCenter5 hr. ago

Pine bark and sponge compounds could counter drug-resistant malaria and babesiosis

Researchers at the University of California, Riverside, along with collaborators at UC Irvine and Yale University, are developing new antiparasitic treatments for malaria and babesiosis. These diseases, caused by parasites that infect red blood cells, are becoming increasingly resistant to existing drugs. The National Institute of Allergy and Infectious Diseases has awarded over $8 million in grants to support this research, with UC Riverside receiving nearly $2.5 million. The study focuses on two compound classes: leelamine-derived isonitriles (LDIs) from pine bark and pyrroloiminoquinones (PIQs) from marine sponges. Both show promise against drug-resistant strains of the pathogens. The research combines expertise in medicinal chemistry, genetics, and systems biology to transform natural compounds into potential medicines.

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Phys.org logoPhys.orgIndependentCenter5 hr. ago
Pine bark and sponge compounds could counter drug-resistant malaria and babesiosis

Researchers at the University of California, Riverside, along with collaborators at UC Irvine and Yale University, are developing new antiparasitic treatments for malaria and babesiosis. These diseases, caused by parasites that infect red blood cells, are becoming increasingly resistant to existing drugs. The National Institute of Allergy and Infectious Diseases has awarded over $8 million in grants to support this research, with UC Riverside receiving nearly $2.5 million. The study focuses on two compound classes: leelamine-derived isonitriles (LDIs) from pine bark and pyrroloiminoquinones (PIQs) from marine sponges. Both show promise against drug-resistant strains of the pathogens. The research combines expertise in medicinal chemistry, genetics, and systems biology to transform natural compounds into potential medicines.

Bias read (Center): The article presents scientific research without overt ideological framing. It discusses medical advancements and funding without taking a partisan stance. While the topic relates to public health policy, the focus is on scientific progress rather than political advocacy. The tone remains neutral,侧重

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