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Polluted air can damage DNA in sperm, a major study shows
Slovenia🌿 EnvironmentCenteryesterday

Polluted air can damage DNA in sperm, a major study shows

A study analyzing DNA in sperm cells from 1220 participants has revealed 39 epigenetic changes linked to air pollution mixtures. The research, led by epidemiologist Carrie Nobles, involved over 2000 men from Salt Lake City who provided multiple sperm samples between 2013 and 2017. Scientists assessed their exposure to external pollutants three months before sample collection—the period during which sperm cells develop. Among the monitored pollutants were ozone, nitrogen dioxide, sulfur dioxide, and fine particulate matter. The strongest associations were found with ozone and nitrogen dioxide. These changes involve methylation of DNA, a process where chemical tags influence gene activity without altering the genetic code itself. Such epigenetic changes could affect sperm quality and potentially embryo development. One of the affected genes, GNAS, was previously linked to poorer sperm quality and fetal development. Researchers caution that these findings do not prove direct effects on fertility but suggest a possible biological mechanism. Further studies are needed to confirm the connection.

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2 reports

Delo logoDeloIndependent🔒Centeryesterday
Polluted air can damage DNA in sperm, a major study shows

A study analyzing DNA in sperm cells from 1220 participants has revealed 39 epigenetic changes linked to air pollution mixtures. The research, led by epidemiologist Carrie Nobles, involved over 2000 men from Salt Lake City who provided multiple sperm samples between 2013 and 2017. Scientists assessed their exposure to external pollutants three months before sample collection—the period during which sperm cells develop. Among the monitored pollutants were ozone, nitrogen dioxide, sulfur dioxide, and fine particulate matter. The strongest associations were found with ozone and nitrogen dioxide. These changes involve methylation of DNA, a process where chemical tags influence gene activity without altering the genetic code itself. Such epigenetic changes could affect sperm quality and potentially embryo development. One of the affected genes, GNAS, was previously linked to poorer sperm quality and fetal development. Researchers caution that these findings do not prove direct effects on fertility but suggest a possible biological mechanism. Further studies are needed to confirm the connection.

Bias read (Center): The article presents scientific findings without overt ideological framing. It focuses on environmental health impacts and does not take a stance on policy, regulation, or political debate. The tone remains neutral, emphasizing the need for further research rather than advocating for specific action

Delo logoDeloIndependent🔒Centeryesterday
Polluted air can damage DNA in sperm, a major study shows

A large study analyzing DNA of sperm samples from 1,220 participants has identified 39 epigenetic changes linked to exposure to air pollutants. The research, led by epidemiologist Carrie Nobles, found that ozone and nitrogen dioxide were most strongly associated with these changes. These epigenetic modifications affect gene expression without altering the genetic code itself, potentially impacting sperm quality and fetal development. While the findings suggest a possible biological mechanism, they do not yet prove a direct impact on fertility. The study was presented at the European Society of Human Reproduction and Embryology congress in London.

Bias read (Center): The article presents scientific findings without overt ideological framing. It reports on a study conducted by researchers and does not take a partisan stance on environmental policies or political agendas. The focus remains on the scientific implications rather than advocacy for specific political,

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